According to this article,
Adobe will be part of the keynote:
Bryan Lamkin, Adobe senior vice president for Web
publishing, said an Adobe executive will participate in
Jobs' keynote address, and several Adobe
representatives will attend. Lamkin said Adobe will
continue to fully participate in Macworld San Francisco,
a January show that he said is better attended by
Adobe customers.
Also, it is likely that Adobe will give a preview of
publishing software running natively in OS X.